Bufo

About Bufo

• Bufo typically refers to 5-MeO-DMT, a psychedelic substance in the tryptamine class
• In modern use, both toad venom extracts and synthetic powder are used, primarily via vaporization
• Effects typically begin within about 5–60 seconds and total duration is generally around 20–40 minutes

Effects

• Reported effects include unity and interconnectedness, time distortion, conceptual thinking, euphoria, and ego loss
• Compared with DMT, it is described as extreme in intensity and very short in duration
• It generally lacks a visual geometry component and tends to produce stronger physical euphoria and stronger transpersonal or mystical-like effects

Risks

• Mental and physical side effects are reported to occur more often than with DMT, including significant anxiety, dysphoria, nausea, and bodily discomfort
• Its safety profile is much less established, and the exact toxic dose is unknown
• Dangerous interactions may occur, particularly with MAOIs and other combinations

Harm reduction

• Use harm reduction practices when using this substance
• Independently research any combination before use
• It is generally presented as more suitable for people with extensive experience with powerful psychedelics and training in their safe use